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In a rat heart inflammation model, sulforaphane ameliorated doxorubicin-induced chronic heart failure [40] and reduced fibrosis and the scores of post-myocardial infarction associated with an increased HO-1 level [41], as well as the positive anti-inflammatory score in acrolein-induced cardiomyopathy [42], the cardiac ischaemia/reperfusion model [43], and cuprizone-induced cardiotoxicity [44]